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A ‘Game Changer’ For Organ Transplants: Blood Type of Donor Kidneys Altered in Breakthrough Research_我的网站

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A |     Breakthrough new research could significantly increase supply of organs for people with rarer blood types waiting for a transplant, reported The Guardian.,A team of scientists from the University of Cambridge have successfully altered the blood type of three donor kidneys. By flushing blood infused with a special enzyme through a human kidney the scientists removed the blood type markers lining the blood vessels of the organ.,The procedure required using a device that is connected with a donor’s kidney to pass oxygenated blood through it - a normothermic perfusion machine. As a result, the organ was converted to type O, considered the universal donor.,Blood Group Compatible,As the blood type of a donor must be compatible with the recipient’s, the new development could increase the supply of kidneys available for transplant.,A kidney from someone with blood type A cannot be transplanted to someone with blood type B, or visa versa. In such a case, the receiving body’s immune system would reject the new organ, interpreting the different blood type as foreign.,So changing the blood type to the universal O would mean the donor organ could be used for people with any blood type.,“Our confidence was really boosted after we applied the enzyme to a piece of human kidney tissue and saw very quickly that the antigens were removed. After this, we knew that the process is feasible, and we just had to scale up the project to apply the enzyme to full-size human kidneys,” Serena MacMillan, a PhD student at the University of Cambridge, said.,Scientists involved in the research, funded by charity Kidney Research UK and due to be published in the British Journal of Surgery, clarified that the outcome might have particular implications for minority ethnic groups.,Science & TechGood News for ABs: Scientists Can Now Change People's Blood Type21 February, 16:34 GMT,Some blood groups such as O Rh positive and B Rh positive are more prevalent among black, Asian and minority ethnic communities. To complicate matters further, some rare blood types are only found within the black, Asian and minority ethnic communities,This typically places them at a disadvantage, as they struggle to find a match. With low donation rates from these populations, stressed the researchers, sometimes such patients wait for as long as over a year for a compatible donor. They cited figures from 2020-21 showing that just over 9% of total organ donations in the UK came from black and minority ethnic donors. On the other hand, black and minority ethnic patients make up 33% of the kidney transplant waiting list.,“It’s very exciting to think about how this could potentially impact so many lives,” added Serena MacMillan.,The “potentially gamechanging” research was applauded by Dr Aisling McMahon, the executive director of research at Kidney Research UK.,The scientists will now test the reintroduction of other blood types and observe how the novel approach in clinical settings.。    

Zhang Han, a spokesperson for the Taiwan Affairs Office of the State Council
    Zhang Han, a spokesperson for the Taiwan Affairs Office of the State Council
The mainland Taiwan Affairs Office on Wednesday slammed Taiwan regional leader Lai Ching-te for once again promoting separatist rhetoric and attempting to seek "Taiwan independence" through military means, while expressing appreciation for Malaysian Prime Minister Anwar Ibrahim's recent remarks affirming that Taiwan is part of China.
Zhang Han, a spokesperson for the State Council Taiwan Affairs Office, made the remarks at a regular press conference in response to questions concerning Lai's comments at an event in Kinmen marking the 68th anniversary of the 1958 artillery battle.
The question noted that Lai had once again hyped a "new two-state theory" and called on people on the island to support so-called "national defense, defend the country and safeguard democracy," while advocating for resistance to reunification through military means.
"Lai Ching-te stubbornly adheres to the separatist position of 'Taiwan independence,' continuously spreads fallacies and distortions advocating 'Taiwan independence,' deliberately twists history, and goes all out to hype the so-called 'China threat,'" Zhang said.
Zhang said Lai has continued to incite anti-China sentiment and confrontation and has attempted to "resist reunification by force" and "seek independence by force," pushing Taiwan step by step toward the danger of conflict.
"He is an out-and-out destroyer of peace across the Taiwan Straits and a creator of crises in the Taiwan Straits," Zhang said.
The spokesperson warned Lai and the Democratic Progressive Party authorities that the historical trend toward reunification cannot be stopped and that attempts to seek "independence" through military means would only accelerate their own demise.
Zhang also called on Taiwan compatriots to recognize the deceptive and harmful nature of Lai's separatist provocations, oppose "Taiwan independence" separatism and take concrete actions to safeguard their own security and well-being as well as peace and stability across the Taiwan Straits.
At the same press conference, Zhang also responded to remarks recently made by Malaysian Prime Minister Anwar Ibrahim concerning the Taiwan question.
It was reported that Anwar said in a recent interview that Taiwan is part of China, drawing an analogy with a hypothetical situation in which a Malaysian state sought to break away, saying that he would likewise defend the sanctity and unity of his country.
Taiwan's so-called "external affairs authority" subsequently claimed that Anwar's remarks had "belittled Taiwan's sovereignty" and could undermine the confidence of Taiwan businesses considering investment in Malaysia.
"We appreciate the position of relevant countries in upholding the one-China principle," Zhang said.
"There is only one China in the world, and Taiwan is an inalienable part of China's territory. There is no such thing as 'Taiwan sovereignty,'" she said.
Zhang accused the DPP authorities of stubbornly adhering to the separatist position of "Taiwan independence," spreading separatist arguments abroad and repeatedly attempting to pressure other countries by invoking trade and investment.
Such behavior, she said, "precisely exposes the essence of their attempt to seek 'independence' through economic means."

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